VITEK^® MS: Product Safety

Routine is Now Extraordinary

VITEK MS is now AOAC RI validated! Certificate number is PTM# 011501. This is the first and only AOAC approved Mass Spec for bacterial identification.

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Overview
Mass Spectrometry
MALDI-TOF
Uses
In the News

ABOUT VITEK MS

VITEK MS for Pharmaceutical Industry:

VITEK MS provides ultra- rapid results:

Directly deposit the microorganism on the target slide, add the ready-to-use matrix solution and insert slide into the VITEK® MS system. Identification results are displayed within minutes.

VITEK MS offers security and traceability:

Not only is VITEK MS 21 CFR Part 11 Compliant, but the VITEK MS includes the VITEK® MS Prep Station, which securely links specimen information with each spot on the target slide. Unique barcodes on the plated media and the VITEK MS target slides offer complete workflow traceability.

VITEK MS provides accurate identification:

The VITEK MS database, which contains a large number of specific microorganisms for the pharmaceutical industry, was developed from multiple regions, countries, sources and environments. In addition, our proprietary algorithm vastly increases the accuracy of identification.

VITEK MS is flexible:

VITEK MS can be integrated into quality control laboratories with either centralized or decentralized workflows by utilizing its unique VITEK MS Prep Station. This flexibility allows multiple users to work in parallel by preparing their own target slides with the capability to identify up to 192 isolates per run.

ABOUT MASS SPECTROMETRY

Mass spectrometry (MS) is an analytical technique for determining the elemental composition of a sample. The MS principle consists of ionizing chemical compounds to generate charged molecules and to measure their mass-to-charge ratio. Such molecular “signatures” can be used for rapid bacterial identification (ID) from isolated colonies. The use of mass spectrometry for bacterial ID is especially suitable and cost-efficient for laboratories with high volumes of samples.

ABOUT MALDI-TOF

MALDI-TOF technology (Matrix Assisted Laser Desorption Ionization Time-of-Flight) used by VITEK MS examines the patterns of proteins detected directly from intact bacteria. The sample to be analyzed is mixed with another compound, called a matrix. The mixture is applied to a metal plate and irradiated with a laser. The matrix absorbs the laser light and vaporizes, along with the sample, in the process gaining an electrical charge (ionization). Electric fields then guide the ions into the time of flight mass spectrometer, which separates them according to their mass to charge (m/z) ratio, and ultimately the quantity of each ion is measured. Detection is achieved at the end of the flight tube.