BACT/ALERT® 3D

Optimizing Collection to Care

The BACT/ALERT 3D instrument is a state-of-the-art, automated microbial detection system. The BACT/ALERT system offers advantages in every dimension of microbial detection testing.

From its space-saving modular design to its easy touch-screen operation and flexible data management options, every size laboratory can perform microbial detection with the BACT/ALERT 3D.

USES

BACT/ALERT 3D is used for detecting the presence or absence of microorganisms in:

  • Blood
  • Sterile body fluids

FEATURES AND BENEFITS

Because it's so easy to use, BACT/ALERT 3D saves time, facilitates cross-training and helps prevent errors. This system offers immediate bottle recognition, putting you in control of bottle loading and unloading and virtually eliminating bottle handling errors during microbial detection testing. The system's automatic, built-in quality control, along with a low false positive rate and a rapid response time of this system, means you do more in less time with greater accuracy.

The latest generation of BACT/ALERT Culture Media brings the most advanced, innovative microbial growth and detection technology to your laboratory. BACT/ALERT media provide unsurpassed performance, in the detection of a wide variety of microorganisms including bacteria, fungi, and yeasts.

With flexible data management options of an automated microbial detection system, and available with many different system options, BACT/ALERT 3D allows you to choose the best configuration for your laboratory.

Plastic Bottles Mean Safety
Safety is an important consideration for any microbial testing. bioMérieux is committed to providing the safest products possible to the microbiology laboratory. BACT/ALERT bottles are made of unbreakable plastic to protect them from breakage. They are also lightweight to reduce the cost of disposal and shipping.

BACT/ALERT 3D: HEALTHCARE FEATURES & SPECS

Results are the most important aspect of any microbial detection system. Built on bioMérieux's patented colorimetric technology, the BACT/ALERT 3D demonstrates unsurpassed recovery of a wide range of organisms.

BACT/ALERT 3D System Options
We've designed a microbial detection system to meet your individual needs. The modular design of the BACT/ALERT 3D enables the most flexible, ergonomic configuration to meet space limitations. The control module manages all bottle inventory and data, while the incubator module performs the testing.

BACT/ALERT 3D Combination Module – The BACT/ALERT 3D Combination Module is an integrated system that uses only 20 inches of bench space. Now, even the smallest laboratories can get the highest-quality microbiology test results on-site.

BACT/ALERT 3D: HEALTHCARE USES

For Clinical Laboratory:

  • Microbial detection
  • Sepsis and quality control testing
  • Monitoring for the presence or absence of microorganisms
  • Data management/integration
  • Instrumentation interfacing

For Clinicians and Administrators:

  • Workload efficiency
  • OSHA guidelines
  • Patient/employee safety
  • Data management/integration
  • Cost savings

Optimized Time to Detection and Microorganism Recovery

The next-generation Fastidious Antimicrobial Neutralization Plus media (FAN Plus) from bioMérieux features optimized time to detection and microorganism recovery with an improved environment that fosters microbial growth for bacteria and yeast.  FAN® Plus media offers effective organism growth from both blood and sterile body fluid samples, along with growth performance guidelines for use in delayed entry conditions.

Fastidious Antimicrobial Neutralization Plus Media (FAN® Plus)

FAN Plus media with Adsorbent Polymeric Beads (APB) to neutralize antimicrobials

Bottle Type Media Formulation Specimen Type Specimen Volume
BACT/ALERT FA Plus
Ref: 410851
30 mL of supplemented complex media containing adsorbent polymeric beads Blood or normally sterile body fluid (SBF) Up to 10 mL
BACT/ALERT FN Plus
Ref: 410852
40 mL of supplemented complex media containing adsorbent polymeric beads Blood or SBF Up to 10 mL
BACT/ALERT PF Plus
Ref: 410853
30 mL of supplemented complex media containing adsorbent polymeric beads Blood Up to 4 mL

 

Standard Media

Bottle Type Media Formulation Specimen Type Specimen Volume
BACT/ALERT SA
Standard Aerobic
Ref: 259789
40 mL supplemented tryptic soy broth (TSB) Blood or normally sterile body fluid (SBF) Up to 10 mL
BACT/ALERT SN
Standard Anaerobic
Ref: 259790
40 mL TSB Blood or SBF Up to 10 mL

 

Mycobacterium Media

Bottle Type Media Formulation Specimen Type Specimen Volume
BACT/AlERT MP Mycobacteria
Process Ref: 259797
Use with Ref: 259760
10 mL supplemented Middlebrook 7H9 broth Processed specimen or SBF other than blood 0.5 mL

 

Platelet QC Testing

Bottle Type Media Formulation Specimen Type Specimen Volume
BACT/ALERT
BPA Aerobic Platelet Culture Bottles
Ref: 423278
40 mL supplemented tryptic soy broth (TSB) Leukocyte reduced apheresis platelet (LRAP) units, and both leukocyte reduced single and a pool of up to six (6) units of leukocyte reduced whole blood platelet concentrates (LRWBPC) 4 - 10 mL
BACT/ALERT
BPN Anaerobic Platelet Culture Bottles
Ref: 423279
40 mL supplemented tryptic soy broth (TSB) Leukocyte reduced apheresis platelet (LRAP) units, and both leukocyte reduced single and a pool of up to six (6) units of leukocyte reduced whole blood platelet concentrate (LRWBPC) 4 - 10 mL

 

Blood Collection

Image Description Product Number Packaging

VACUETTE® Blood Culture Holder
Neck design accommodates evacuated tubes without the need for an insert. (Female threaded Luer)

Ref: 450181 320 per box

ITL SampLok® Adapter Cap 3

Ref: A100760 560 per box

ITL SampLok® Adapter Cap 3 Insert

Ref: A100761 840 per box

 

 

BACT/ALERT 3D: HEALTHCARE SOFTWARE

BACT/ALERT 3D Signature:

The BACT/ALERT 3D Signature is a powerful microbiology workstation with comprehensive capabilities. It is ideal for higher-volume laboratories, university settings, or where expanded flexibility in operating routines, reporting and data management are needed.

BACT/ALERT 3D Select:

The ideal choice for routine microbial testing in areas where expanded data management or laboratory information system (LIS) connectivity is not needed.

BACT/ALERT 3D SelectLink:

The perfect option for routine microbial testing where exchange of basic data and results with the LIS is a necessity.

Standard vs. FAN® Media

Weinstein MP, Mirrett S, Reimer LG, Wilson ML, Smith-Elekes S, Chuard CR, Joho KL, Reller LB. Controlled evaluation of BACT/ALERT standard aerobic and FAN® aerobic blood culture bottles for detection of bacteremia and fungemia. J Clin Microbiol. 1995;33(4):978-981.

Wilson ML, Weinstein MP, Mirrett S, Reimer LG, Feldman RJ, Chuard CR, Reller LB. Controlled evaluation of BACT/ALERT® standard anaerobic and FAN® anaerobic blood culture bottles for the detection of bacteremia and fungemia. J Clin Microbiol. 1995;33(9):2265-2270.

McDonald LC, Fune J, Gaido LB, Weinstein MP, Reimer LG, Flynn TM, Wilson ML, Mirrett S, Reller LB. Clinical importance of increased sensitivity of BACT/ALERT® FAN® aerobic and anaerobic blood culture bottles. J Clin Microbiol. 1996;34(9):2180-2184.

Mirrett S, Everts RJ, Reller LB. Controlled Comparison of Original Vented Aerobic FAN® Medium with New Nonvented BACT/ALERT® FA Medium for Culturing Blood. J Clin Microbiol. 2001;39(6):2098-2101.

Mirrett S, Petti CA, Woods CW, Magadia R, Weinstein MP, Reller LB. Controlled Clinical Comparison of the BACT/ALERT® FN and the Standard Anaerobic SN Blood Culture Medium. J Clin Microbiol. 2004;42(10):4581-4585.

FAN vs. BACTEC Plus

Ziegler R, Johnscher I, Martus P, Lenhardt D, Just HM. Controlled clinical laboratory comparison of two supplemented aerobic and anaerobic media in automated blood culture systems to detect bloodstream infections. J Clin Microbiol. 1998; 36(3):657-661.

Pohlman JK, Kirkley BA, Easley KA, Basille BA, Washington JA. Controlled clinical evaluation of BACTEC Plus Aerobic/F and BACT/ALERT® aerobic FAN® bottles for detection of bloodstream infections. J Clin Microbiol. 1995;33(11):2856-2858.

Jorgensen JH, Mirrett S, McDonald LC, Murray PR, Weinstein MP, Fune J, Trippy CW, Masterson M, Reller LB. Controlled clinical laboratory comparison of BACTEC Plus Aerobic/F Resin medium with BACT/ALERT® Aerobic FAN® medium for detection of bacteremia and fungemia. J Clin Microbiol. 1997;35(1):53-58.

FAN® Plus Media

Altun O, Almuhayawi M, Ullberg M and Ozenci V, Clinical Evaluation of the FilmArray Blood Culture Identification Panel in Identification of Bacteria and Yeasts from Positive Blood Culture Bottles, J. Clin. Microbiol. 2013, 51(12):4130.

Amarsy-Guerle R, Mougari F, Jacquier H, Oliary J, Benmansour H, Riahi J, Bercot B, Raskine L and Cambau E. High medical impact of implementing the new polymeric bead-based BACT/ALERT® FA Plus and FN Plus blood culture bottles in standard care, Eur J Clin Microbiol Infect Dis. 2015 Feb. Doi: 10.1007/s10096-015-2319-8

Kirn TJ, Mirrett S, Reller LB, Weinstein MP, Controlled Clinical Comparison of BACT/ALERT FA Plus and FN Plus Blood Culture Media with BACT/ALERT FA and FN Blood Culture Media, J. Clin. Microbiol. doi:10.1128/JCM.03063-13.

Lee DH, Kim SC, Bae IG, Kim S, Clinical Evaluation of BACT/Alert FA Plus and FN Plus Bottles Compared with Standard Bottles, J. Clin. Microbiol. 2013, 51(12):4150.

Mitteregger D, Barousch W, Nehr M, Kundi M, Zeitlinger M , Makristathis A and Hirschl AM, Neutralization of Antimicrobial Substances in New BACT/Alert FA and FN Plus Blood Culture Bottles, J. Clin. Microbiol. 2013, 51(5):1534.

Doern C, Mirrett S, Halstead D, Abid J, Okada P and Reller B. Controlled Clinical Comparison of New Pediatric Medium with Adsorbent Polymeric Beads (PF Plus) versus Charcoal-Containing PF Medium in the BACT/Alert Blood Culture System. J. Clin. Microbiol. 2014 52(6): 1898-1900.

FAN Plus Media vs. BACTEC Plus

Fiori B, D'Inzeo T, Di Florio V, De Maio F, De Angelis G, Giaquinto A, Campana L, Tanzarella E, Tumbarello M, Antonelli M, Sanguinetti M, Spanu T. Performance of Two Resin-Containing Blood Culture Media in Detection of Bloodstream Infections and in Direct Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) Broth Assays for Isolate Identification: Clinical Comparison of the BACT/Alert Plus and Bactec Plus Systems. J. Clin. Microbiol. 2014 52(10): 3558-3567

Standard Media Recovery

Mirret S, Reller LB, Petti CA, Woods CW, Vazirani B, Sivadas R, and Weinstein MP. Controlled Clinical Comparison of BACT/ALERT® Standard Aerobic Medium with BACTEC Standard Aerobic Medium for Culturing Blood. J. Clin Microbiol. 2003; 41(6):2391-2394.

Bernard D, Verschraegen G, Claeys G, Lauwers S, Rosseel P. Bilophila wadsworthia bacteremia in a patient with gangrenous appendicitis. Clin Infect Dis. June 1994;18:1023-1024.

Body Fluids

Bourbeau P, Riley J, Heiter BJ, Master R, Young C, Pierson C. Use of the BACT/ALERT® blood culture system for culture of sterile body fluids other than blood. J Clin Microbiol. 1998;36(11):3273-3277.

Alfa MJ, Degagne P, Olson N, Harding KM. Improved detection of bacterial growth in continuous ambulatory peritoneal dialysis effluent by use of BACT/ALERT® FAN® bottles. J Clin Microbiol. 1997;35(4):862-866.

Glass vs. Plastic Bottles

Snyder JW, Munier GK, Bostic GD, Bozigar PS, Hanna R. Evaluation of a Plastic Nonvented Aerobic Blood Culture bottle for Use with the BACT/ALERT® Microbial Detection System. J Clin Microbiol 2002; 40(12): 4757-4759.

Petti, CA, Mirrett S, Woods CW, and Reller LB. Controlled Clinical Comparison of Plastic versus Glass Bottles of BACT/ALERT® PF Medium for Culturing Blood from Children. J Clin Microbiol 2005; 43(1): 445–447

Petti CA, Mirrett S, Woods CW, Reller LB, Controlled clinical comparison of plastic and glass bottles of BACT/ALERT® FA medium for culturing organisms from blood of adult patients. J Clin Microbiol 2005; 43(4), 1960-1962

Pediatric

Alpern E, Alessandrini E, Bell L, Shaw K, McGowan L. Occult bacteremia from a pediatric emergency department: current prevalence, time to detection, and outcome. Pediatrics. 2000;106(3):505-511.

McGowan K, Foster J, Coffin S. Outpatient pediatric blood cultures: time to positivity. Pediatrics. 2000;106(2):251-255.

Krishner KK, Gibb P, CorbettS, and Church DEIDRE. Comparison of the BACT/ALERT® PF Pediatric FAN® Blood Culture Bottle with the Standard Pediatric Blood Culture Bottle, the Pedi-BACT J Clin Microbiol. 2001;39(8): 2880-2883.

BACT/ALERT vs. ESP

Welby-Sellenriek PL, Keller DS, Ferrett RJ, Storch GA. Comparison of the BACT/ALERT® FAN® aerobic and the Difco ESP 80A aerobic bottles for pediatric blood cultures. J Clin Microbiol. 1997;35(5):1166-1171.

Doern G, Barton A, Rao S. Controlled comparative evaluation of BACT/ALERT® FAN® and ESP 80A aerobic media as means for detecting bacteremia and fungemia. J Clin Microbiol. 1998; 35(9):2686-2689.

Mycobacteria, Yeast and Fungi

Alcaide F, Benitez MA, Escriba JM, Martin R. Evaluation of the BACTEC MGIT™ 960 and the MB/BACT systems for recovery of mycobacteria from clinical specimens and for species identification by DNA AccuProbe. J Clin Microbiol. 2000;38(1):398-401.

Crump J, Tanner DC, Mirrett S, McKnight CM, Reller LB, Controlled Comparison of BACTEC 13A, Myco/F Lytic, BACT/ALERT® MB and Isolator 10 Systems for Detection of Mycobacteremia. J Clin Microbiol 2003;41(5):1987-1990.

McDonald, L., Weinstein, M., Fune, J., Mirrett, S., Reimer, L., Reller, B., Controlled Comparison of BACT/ALERT® FAN® Aerobic Medium and Bactec Fungal Blood Culture Medium for Detection of Fungemia, J Clin Microbiol 2001:39(2): 622–624.

Other

Bourbeau P and Foltzer M. Routine Incubation of BACT/ALERT FA and FN Blood Culture Bottles for More than 3 Days May Not Be Necessary. J Clin Microbiol. 2005: 43(5): 2506-2509.

Seegmuller I, Eschenbach U, Kamereck K. Sensitivity of the BACT/ALERT® FA medium for detection of Pseudomonas aeruginosa in pre-incubated blood cultures and its temperature dependence. J Med Microbiol, (2004); 53. 869-874.

 

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